Jasmine for Skin

Several clinical trials and randomized controlled trials (RCTs) have investigated the potential benefits of jasmine for skin health. Jasmine, known for its fragrant flowers and diverse chemical composition, has been explored as a potential therapeutic agent for various skin conditions. This introduction will briefly overview the existing research examining the application of jasmine in dermatological contexts before delving into a more detailed analysis of the findings.

Protocols Studied in Research

[1] Facebook usage on young women's mood and body image. (Cited by: 89) (pmid: 25615425)

• Protocol: A randomized controlled trial assigned 112 women to browse Facebook, a fashion magazine website, or a neutral website for 10 minutes. Mood, body dissatisfaction, and appearance discrepancies were measured afterward, along with appearance comparison tendency.
• Outcome: Facebook use correlated with a more negative mood compared to the control. Women with high appearance comparison tendencies reported more facial, hair, and skin-related discrepancies after Facebook exposure than the control.

[2] Jasmine rice panicle extract for skin aging. (Cited by: 15) (pmid: 27721049)

• Protocol: A randomized, double-blind, placebo-controlled study with 24 Thai volunteers. Topical creams containing 0.1-0.2% jasmine rice panicle extract were applied daily for 84 days. In vitro studies assessed cytotoxicity, melanogenesis inhibition, and antioxidant activity.
• Outcome: Jasmine rice panicle extract, rich in phenolic acids, was safe and significantly improved skin hydration, reduced wrinkles, and lightened skin. Effects were comparable between 0.1% and 0.2% concentrations.

[3] Alpha-tocopherol and L-selenomethionine supplementation for the prevention of non-melanoma skin cancer in individuals with arsenical skin lesions. (Cited by: 28) (pmid: 23590571)

• Protocol: A 6-year, double-blind, randomized controlled trial (7000 participants with arsenical skin lesions in Bangladesh) testing the efficacy of daily alpha-tocopherol (100mg) and L-selenomethionine (200mcg) supplementation.
• Outcome: The study found associations between arsenical skin lesion severity and several comorbidities (hypertension, diabetes, asthma, peptic ulcer disease), but did not report the effect of the intervention on skin cancer prevention. Further analysis of the intervention's effect is needed.

[4] Aromatherapy massage with jasmine oil for assessing autonomic and subjective arousal levels. (Cited by: 11) (pmid: 20184043)

• Protocol: A randomized controlled trial with 40 healthy volunteers. Participants received either jasmine oil or a placebo applied topically to the abdomen. Physiological parameters (blood pressure, pulse, etc.) and subjective emotional ratings were measured.
• Outcome: Jasmine oil significantly increased physiological arousal (breathing rate, blood oxygen saturation, blood pressure) and subjective arousal (alertness, vigor), suggesting a stimulating rather than relaxing effect, potentially useful for treating depression.

[5] Mediation analysis to determine if trans-eQTL associations are mediated by cis-eQTLs. (Cited by: 51) (pmid: 25474530)

• Protocol: Genome-wide association study of SNPs and gene expression in 1799 Bangladeshi individuals; Sobel tests used for mediation analysis; replication attempted in two European cohorts; simulations conducted to assess impact of measurement error.
• Outcome: A substantial fraction of observed trans-eQTL associations are explained by cis-mediation; cis-mediation can significantly attenuate or alter trans-eQTL associations; measurement error can mask complete mediation.

[6] Cosmetic cream (with or without plant extracts) on dermal extracellular matrix components in women aged 45-65. (Cited by: 10) (pmid: 20636999)

• Protocol: A randomized, controlled trial where 24 women applied a cosmetic cream with soy and jasmine extracts (B) to one arm and a vehicle cream (A) to the other for 3 months. Multiphoton tomography measured changes in dermal matrix.
• Outcome: Cream B significantly increased extracellular matrix signal in the deeper upper dermis after 12 weeks, suggesting increased collagen and elastin, while cream A showed no effect. This is the first in vivo demonstration of a cosmetic product's effect on the superficial dermis using this non-invasive method.

[7] Shufeng Liangxue Decoction (SLD) for hormone dependence dermatitis (HDD). (Cited by: 2) (pmid: 19317172)

• Protocol: A randomized controlled trial of 116 HDD patients compared SLD plus standard Western medication (loratadine, calglucon, vitamin C) to standard Western medication alone. Treatment lasted 4 weeks.
• Outcome: SLD plus Western medication showed significantly higher cure/improvement rates and a lower relapse rate than Western medication alone after 3 months. SLD was well-tolerated.

Research Interpretation: Summary and Conclusion

The reviewed studies employed diverse methodologies, including randomized controlled trials (RCTs), in vitro studies, and genome-wide association studies, investigating various aspects of jasmine's effects. While some studies focused on jasmine's psychological effects (increased arousal), others explored topical applications of jasmine extracts (or jasmine-containing creams) demonstrating improved skin hydration, wrinkle reduction, skin lightening, and increased dermal matrix signal suggesting boosted collagen and elastin production. A key variation lies in the specific jasmine components used; some studies utilized jasmine oil, while others employed jasmine rice panicle extract or jasmine extracts within cosmetic creams. The studies lacked consistency in the form of jasmine used, making direct comparisons challenging. However, the evidence suggests potential benefits of jasmine-derived components for both mood and skin health, warranting further research to standardize jasmine preparations and investigate their mechanisms of action. The inconsistent findings highlight the need for more rigorous, well-designed studies using standardized jasmine extracts to confirm and expand upon these preliminary results.

Publications

[1] Fardouly J; Diedrichs PC; Vartanian LR; Halliwell E (2015). Social comparisons on social media: the impact of Facebook on young women's body image concerns and mood Body image 13 :38-45.

[2] Kanlayavattanakul M; Lourith N; Chaikul P (2016). Jasmine rice panicle: A safe and efficient natural ingredient for skin aging treatments Journal of ethnopharmacology 193 :607-616.

[3] Argos M; Rahman M; Parvez F; Dignam J; Islam T; Quasem I; K Hore S; T Haider A; Hossain Z; I Patwary T; Rakibuz-Zaman M; Sarwar G; La Porte P; Harjes J; Anton K; Kibriya MG; Jasmine F; Khan R; Kamal M; Shea CR; Yunus M; Baron JA; Ahsan H (2013). Baseline comorbidities in a skin cancer prevention trial in Bangladesh European journal of clinical investigation 43 (6) :579-88.

[4] Hongratanaworakit T (2010). Stimulating effect of aromatherapy massage with jasmine oil Natural product communications 5 (1) :157-62.

[5] Pierce BL; Tong L; Chen LS; Rahaman R; Argos M; Jasmine F; Roy S; Paul-Brutus R; Westra HJ; Franke L; Esko T; Zaman R; Islam T; Rahman M; Baron JA; Kibriya MG; Ahsan H (2014). Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians PLoS genetics 10 (12) :e1004818.

[6] Bazin R; Flament F; Colonna A; Le Harzic R; Buckle R; Piot B; Laize F; Kaatz M; Konig K; Fluhr JW (2010). Clinical study on the effects of a cosmetic product on dermal extracellular matrix components using a high-resolution multiphoton tomograph Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 16 (3) :305-10.

[7] Bai YS; Zhou CY; Wang JQ (2008). [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction] Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 28 (12) :1121-3.