PDRN for Skin

Polydeoxyribonucleotides (PDRNs) promote tissue regeneration by enhancing cell growth, extracellular matrix production, angiogenesis, and reducing inflammation via adenosine A₂A receptor activation.

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Research Interpretation

Polydeoxyribonucleotides (PDRNs) are low molecular weight DNA-derived molecules that support tissue regeneration and wound healing. Research shows they enhance cell migration and growth, stimulate extracellular matrix protein production, promote angiogenesis, and reduce inflammation through adenosine A₂A receptor activation. PDRNs have demonstrated benefits in skin rejuvenation, impaired wound healing, and musculoskeletal tissue repair, improving healing time, tissue quality, and reducing pain. Derived from sources like salmon sperm, they are considered safe, with ongoing studies aiming to standardize dosages and expand clinical applications.

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