Castor Oil for Wrinkles

Castor oil, a natural emollient derived from the castor bean plant, has garnered attention for its potential application in wrinkle reduction. Several clinical trials and randomized controlled trials (RCTs) have investigated the efficacy of castor oil in addressing wrinkles, exploring its purported ability to improve skin hydration and potentially stimulate collagen production.

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Research Interpretation

Protocols Studied in Research

[1] Topical castor oil cream for infraorbital hyperpigmentation. (Cited by: 1) (pmid: 37927123)

  • Protocol: A single-arm clinical trial enrolled 22 patients with infraorbital hyperpigmentation who applied castor oil cream twice daily for two months. Measurements included VisioFace and SkinColorCatch device readings and a visual analog scale.
  • Outcome: Castor oil cream significantly reduced infraorbital hyperpigmentation, melanin levels, wrinkles, and skin laxity. Larger, randomized trials are needed to confirm these findings.

Research Interpretation: Summary and Conclusion

The available evidence on the efficacy of castor oil for wrinkle reduction is limited to a single small, single-arm clinical trial (PMID 37927123). This study, involving 22 participants with infraorbital hyperpigmentation, investigated the effects of twice-daily application of castor oil cream for two months. Positive outcomes were observed, showing significant reductions in infraorbital hyperpigmentation, melanin levels, wrinkles, and skin laxity, as measured by VisioFace and SkinColorCatch devices and a visual analog scale. However, the lack of a control group and the small sample size necessitate caution in interpreting these results. Larger, randomized controlled trials are needed to confirm the efficacy and safety of castor oil cream for wrinkle reduction and to determine the optimal application method and duration of treatment.

Publications

[1] Parvizi MM; Saki N; Samimi S; Radanfer R; Shahrizi MM; Zarshenas MM (2024). Efficacy of castor oil cream in treating infraorbital hyperpigmentation: An exploratory single-arm clinical trial Journal of cosmetic dermatology 23 (3) :911-917.